Aldehyde reductase is a major protein associated with 3-deoxyglucosone reductase activity in rat, pig and human livers.

نویسندگان

  • T Kanazu
  • M Shinoda
  • T Nakayama
  • Y Deyashiki
  • A Hara
  • H Sawada
چکیده

3-Deoxyglucosone reductase activity in the extracts of rat, pig and human livers was potently inhibited by aldehyde reductase inhibitors. The major species of 3-deoxyglucosone reductase purified from human and pig livers were biochemically and immunochemically identical with aldehyde reductase. The two enzymes and rat liver aldehyde reductase exhibited higher catalytic efficiency for 3-deoxyglucosone than for D-glucuronate, a representative substrate of aldehyde reductase.

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عنوان ژورنال:
  • The Biochemical journal

دوره 279 ( Pt 3)  شماره 

صفحات  -

تاریخ انتشار 1991